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Genetic Circuits

All articles tagged with #genetic circuits

science-and-technology1 year ago

"Unlocking the Power of Genetic Circuits on Single DNA Molecules"

Researchers have explored the construction of genetic circuits on single DNA molecules, demonstrating localized protein synthesis as a guiding principle for dissipative nanodevices, offering insights into artificial cell design and nanobiotechnology applications. The study focuses on reconstituting biological processes outside living cells, aiming to improve understanding of nature's guiding principles and construct future artificial cells. By leveraging localized protein synthesis, the researchers envision enhancing the functionality of artificial cells constructed from single DNA molecules and exploring potential applications in self-encoded nanodevices.

health-medical-research2 years ago

"Programmable mRNA Therapy for Solid Tumor Treatment Undergoes Testing"

Scientists are planning to test a new cancer treatment using mRNA, which has been successful in Covid-19 vaccines. The treatment, developed by Strand Therapeutics, involves programming mRNA to produce an inflammatory protein called interleukin-12 (IL-12) that triggers the immune system to attack cancer cells. The mRNA is designed to self-destruct if it goes to unintended locations, and initial trials will focus on melanoma and breast cancer. This approach aims to address the challenge of delivering mRNA to specific locations in the body and could potentially revolutionize cancer therapy.