"Exercise Mimetics: The Promise of Fitness Benefits in a Pill"
Scientists in the US have developed a potential "exercise pill," called SLU-PP-332, that mimics some of the benefits of exercise by targeting a natural metabolic pathway usually triggered by physical activity. In experiments on mice, the drug improved muscle function, fitness, and endurance without requiring increased physical activity. The drug's development represents a breakthrough in targeting a previously thought "undruggable" metabolic pathway, with potential applications for treating diseases like neurodegenerative conditions and heart failure. While not a perfect substitute for exercise, the pill shows promise in conveying exercise benefits to various organs and tissues, and may be particularly beneficial for individuals unable to exercise due to aging, certain diseases, or muscle loss.
