All articles tagged with #embryogenesis
The article introduces spatial-DMT, a novel technology for simultaneous spatial profiling of DNA methylome and transcriptome in tissue sections at near single-cell resolution, applied to mouse embryos and brains, revealing intricate gene regulation mechanisms during development and tissue-specific epigenetic landscapes.
Researchers have successfully cultivated primate embryos in a lab for 25 days post-fertilization, achieving key developmental landmarks never before observed in culture, including the start of organ development. This breakthrough could help understand congenital birth defects and organ development in humans. The embryos surviving to 25 days had many of the hallmarks of an in utero embryo, such as the three embryonic tissue layers ultimately responsible for the formation of the fetus and the formation of the neural tube, which goes on to form the brain and spinal cord.