Tag

Drugdiscovery

All articles tagged with #drugdiscovery

technology1 year ago•5 min saved

Lessons from Navigating AI in Biotechnology

Naren Tallapragada, CEO of Tessel Bio, discusses the limitations and potential of AI in biology, emphasizing that while AI models like AlphaFold have advanced protein folding predictions, they cannot yet fully model biological systems such as cells or tissues. He highlights the importance of real data, as seen in successful startups like Fauna Bio and Enveda, which have built extensive databases to support their AI models. Tallapragada advocates for "augmented intelligence," where AI assists in guiding experiments, as a practical approach in drug discovery.

via STAT|

#ai #biotechnology #datascience

technology1 year ago•2 min saved

DeepMind Open-Sources AlphaFold 3, Revolutionizing Protein Prediction

Google DeepMind has open-sourced AlphaFold 3, allowing academic researchers access to its training weights for non-commercial use. This model, released in May 2024, predicts protein structures with 50% better accuracy and is expected to revolutionize drug discovery. Isomorphic Labs, a sister company, aims to leverage AI for drug development, with partnerships with major pharmaceutical companies like Eli Lilly and Novartis. AlphaFold has already predicted over 200 million protein structures, significantly advancing biomedical research.

via AIM|

#alphafold #deepmind #drugdiscovery

businesstechnology2 years ago•0 min saved

"Alphabet's Isomorphic Secures Drug Discovery Deals with Eli Lilly and Novartis Worth $2.98B"

Isomorphic Labs, an AI startup under Alphabet, has announced partnerships with pharmaceutical giants Eli Lilly and Novartis in deals potentially worth up to $3 billion. The company, led by CEO Demis Hassabis, aims to leverage AI technology from Google DeepMind, such as the AlphaFold model, to accelerate drug discovery. Isomorphic Labs has been rapidly growing in the AI biotech sector since its inception in November 2021 and currently has a significant presence in London and Lausanne.

via Endpoints News|

##alphabet #businesstechnology

health-and-medicine2 years ago•3 min saved

"Zosurabalpin: A New Antibiotic Breakthrough Battles Drug-Resistant Superbugs"

Swiss scientists have discovered a new antibiotic, zosurabalpin, which is effective against drug-resistant gram-negative bacteria, specifically targeting Acinetobacter baumannii. This breakthrough, the first in over 50 years, could combat the growing issue of antimicrobial resistance, which is responsible for millions of deaths annually. Zosurabalpin operates by blocking the bacteria's ability to form a protective outer membrane, leading to its death. Currently in phase 1 clinical trials, this discovery opens the door to potentially treating a range of drug-resistant infections and is a significant step forward in the fight against the "silent pandemic" of antibiotic resistance.

via New York Post |

##acinetobacterbaumannii #antibioticresistance

science-and-technology2 years ago•5 min saved

"Unveiling AI's Mysteries: Scientists Reveal Surprising Insights"

Researchers at the University of Bonn have made a breakthrough in understanding how AI, specifically Graph Neural Networks (GNNs), operates in drug discovery. Their study reveals that these AI models tend to rely on memorizing data rather than learning chemical interactions, challenging the expectation that GNNs understand the underlying protein-ligand interactions. This insight could lead to improvements in AI applications for drug research and contributes to the field of Explainable AI, aiming to demystify the decision-making processes of complex AI systems.

via SciTechDaily|

##ai #drugdiscovery