All articles tagged with #cold spring harbor laboratory
Dr. James D. Watson was a pioneering scientist known for co-discovering the structure of DNA, leading Cold Spring Harbor Laboratory, and advancing genetic research and education, though his later controversial remarks led to his separation from the institution.
Cold Spring Harbor Laboratory researchers have discovered that tomato and Arabidopsis thaliana plants use different regulatory systems to control the same gene, linked to genetic makeovers over 125 million years of evolution. Mutations in the CLV3 gene can dramatically increase fruit size, but the specific areas of the gene that need to be disrupted differ between the two plants, indicating divergent evolution. Understanding these genetic differences could make crop genome engineering more predictable and beneficial for farmers and plant breeders.
Researchers at Cold Spring Harbor Laboratory have reprogrammed T cells to fight aging by targeting senescent cells, which are linked to age-related diseases. Using CAR T cells, the team found that a single treatment in mice led to lifelong effects, including improved metabolism and physical activity without tissue damage or toxicity. This breakthrough could potentially offer a one-time treatment for chronic conditions like obesity and diabetes, with implications for human longevity.