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Cisplatin

All articles tagged with #cisplatin

health1 year ago

Chemotherapy Tied to Hearing Loss in Cancer Survivors, Study Reveals

A study from the University of South Florida and Indiana University found that the chemotherapy drug cisplatin can cause significant and potentially progressive hearing loss in cancer survivors, particularly those treated for testicular cancer. The research tracked 100 survivors over an average of 14 years, revealing that 78% experienced notable hearing difficulties. Higher doses and pre-existing cardiovascular conditions increased the risk. The study underscores the need for patients to discuss potential hearing loss with healthcare providers and consider regular hearing evaluations during treatment.

via Fox News|
#cancer-treatment#chemotherapy#cisplatin
health2 years ago

Cancer treatment centers face critical drug shortages.

Shortages of chemotherapy drugs cisplatin and carboplatin have disrupted cancer treatments across the US, including in Pittsburgh. The FDA temporarily shut down platinum drug shipments from a factory in India in December 2022, the primary supplier. The FDA is collaborating with Qilu Pharmaceutical Co. in China and Apotex in Canada to increase the availability of the drugs. Managing the shortage, hospitals are seeking alternative sources for medicines that are in short supply and adjusting chemotherapy regimens for impacted patients.

via TribLIVE|
#cancer-treatment#carboplatin#cisplatin
health2 years ago

Iowa Dad's Battle with Stage Four Pancreatic Cancer and Access to Life-Saving Chemo

A father-of-two in Iowa with stage four pancreatic cancer was nearly left without his life-saving chemotherapy because of the national drug shortage. Ryan Dwars had been receiving chemotherapy for his cancer since December last year but just two days before his final four rounds of treatment, doctors called to say they did not have enough of the chemotherapy drug left for him. Mr Dwars was using cisplatin, which has been in shortage in the US since February. More than 90 percent of hospitals now have the drug in short supply and are opting for alternatives.

via Daily Mail|
#angels-for-change#cancer#chemotherapy
health2 years ago

Cancer patients across the US face medication shortages and delayed treatment.

A nationwide shortage of Cisplatin, a platinum-based infusion cancer treatment, is causing delays in life-sustaining cancer treatments, leaving patients and their families anxious. Michael Griffith, diagnosed with stage 4 cholangiocarcinoma, was receiving infusions with a combination of three medications but was recently told Cisplatin was no longer available, and now his cancer has grown. Kaiser Permanente, Griffith’s treatment provider, told KCRA 3 in a statement that the shortage is impacting all pharmacies in the United States and is a result of numerous factors, including the closure of a major manufacturing plant due to operational issues identified by the FDA.

via KCRA Sacramento|
#cancer#cisplatin#fda
medical2 years ago

"Combination Therapy Shows Promise in Advanced Biliary Tract Cancer Treatment"

Pembrolizumab, an immune checkpoint inhibitor, in combination with gemcitabine and cisplatin, has been found to improve overall survival in patients with advanced biliary tract cancer compared to gemcitabine and cisplatin alone, according to a phase 3 trial. The study involved 1,069 patients and found that the pembrolizumab group had a median overall survival of 12.7 months compared to 10.9 months in the placebo group. The combination therapy could be a new treatment option for patients with previously untreated metastatic or unresectable biliary tract cancer.

via The Lancet|
#biliary-tract-cancer#cisplatin#gemcitabine