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Chlamydia Pneumoniae

All articles tagged with #chlamydia pneumoniae

science1 day ago•6 min saved

Eye-dwelling bacteria linked to Alzheimer's risk could aid early detection

A Nature Communications study found higher levels of the bacterium Chlamydia pneumoniae in retinal tissue of people with Alzheimer's disease, with greater bacterial burden associated with more severe cognitive decline. The findings, supported by lab and mouse models, suggest retinal infection and inflammation may reflect brain pathology and that APOE4 carriers had higher retinal bacterial levels, pointing to retinal imaging as a potential noninvasive biomarker and possible infection-targeted therapies.

via Medical News Today|

#alzheimers-disease #apoe4 #chlamydia-pneumoniae

health-and-medicine4 days ago•6 min saved

Eye-Window to Alzheimer's: Pneumonia Bacterium Linked to Neurodegeneration

A Cedars-Sinai study shows Chlamydia pneumoniae can invade the retina and brain, triggering inflammation, nerve cell loss, and amyloid-beta buildup linked to Alzheimer's; higher bacterial levels correlate with worse cognition, especially in APOE4 carriers. The research suggests chronic infection and inflammation could drive Alzheimer's, and the retina might serve as a noninvasive window for early detection and new treatments targeting infection and inflammation.

via ScienceDaily|

#alzheimers-disease #amyloid-beta #chlamydia-pneumoniae

science8 days ago•6 min saved

Retinal Chlamydia pneumoniae Tied to Faster Alzheimer’s Progression

A Cedars-Sinai study found the pneumonia-causing bacterium Chlamydia pneumoniae in the retina, with higher bacterial loads in individuals with Alzheimer’s disease; the bacteria may amplify brain pathology by triggering the NLRP3 inflammasome, increasing inflammation and amyloid beta, and the retina could serve as a noninvasive biomarker for disease status while anti-inflammatory or antibiotic strategies are being explored, though questions remain about how and when infection occurs.

via Indian Defence Review|

#alzheimers-disease #chlamydia-pneumoniae #inflammation

science20 days ago•4 min saved

Retinal Bacteria May Signal Alzheimer's Progress

A Cedars-Sinai study finds Chlamydia pneumoniae in the retina—more abundant in people with Alzheimer's—where infection correlates with cognitive decline. Lab tests in neurons and animal models show infection-driven inflammation, neuron death, and amyloid-beta buildup, suggesting retinal infection could reflect brain pathology and serve as a noninvasive biomarker and potential treatment target, though causality is not proven.

via ScienceAlert|

#alzheimers-disease #apoe-gene #chlamydia-pneumoniae