Tag

C9orf72

All articles tagged with #c9orf72

Autoimmune Mechanisms in ALS Reveal New Disease Insights

Originally Published 3 months ago — by Nature

The study identifies C9orf72 as a major autoantigen targeted by CD4+ T cells in ALS patients, with responses skewed towards an anti-inflammatory profile, especially in those with longer survival, suggesting a potential protective immune component in ALS progression.

health medical-research als autoimmune-response c9orf72 medical-research neurodegeneration t-cells

New Research Suggests ALS Is Driven by Autoimmune Attack on Nervous System

Originally Published 3 months ago — by Bloomberg.com

Researchers have discovered that in ALS, immune cells attack a neuronal protein called C9orf72, triggering inflammation and nerve cell loss, with variations in immune response linked to disease progression, opening new avenues for targeted therapies that could also impact other neurodegenerative diseases.

health health als autoimmune-response c9orf72 health immune-system neurodegeneration