A study conducted by Northwestern University has found that temporary sleep deprivation, such as pulling an all-nighter, can have antidepressant effects and rewire the brain. The study, conducted on mice, showed that even one night of sleep deprivation led to hyperactive, hypersexual, and aggressive behaviors, as well as increased activity in dopamine neurons. The researchers identified the prefrontal cortex as the region responsible for the antidepressant effects of sleep deprivation. However, the benefits are short-lived, and chronic sleep deprivation can have detrimental long-term effects on cognitive health and mental well-being.
A study conducted by US researchers found that missing out on a night's sleep can have surprising effects on behavior, including an increase in feelings of happiness for several days. The researchers discovered that sleep deprivation rewires the brain, leading to an increase in the feel-good hormone dopamine. While it may temporarily increase sexual arousal and aggression, the overall effect is an antidepressant one. However, the researchers caution against regularly pulling all-nighters and emphasize the importance of a good night's sleep for overall well-being.
A study conducted by the Perelman School of Medicine at the University of Pennsylvania has found that one night of total sleep deprivation can lead to mood improvement in some individuals with depressive disorders. The study used brain imaging to map activity in different regions and found that sleep deprivation enhanced connectivity between the amygdala and the anterior cingulate cortex, which correlated with better mood in both healthy individuals and those with depression. The findings suggest that targeting this brain network could be a potential intervention for antidepressant treatment.