The Surprising Antidepressant Effects of Sleep Deprivation
A study conducted by the Perelman School of Medicine at the University of Pennsylvania has found that one night of total sleep deprivation can lead to mood improvement in some individuals with depressive disorders. The study used brain imaging to map activity in different regions and found that sleep deprivation enhanced connectivity between the amygdala and the anterior cingulate cortex, which correlated with better mood in both healthy individuals and those with depression. The findings suggest that targeting this brain network could be a potential intervention for antidepressant treatment.
