Tag

Agitation

All articles tagged with #agitation

Alzheimer’s Agitation: A Brain Change Often Mistaken for Burnout
health8 days ago

Alzheimer’s Agitation: A Brain Change Often Mistaken for Burnout

The article explains that agitation is a common, brain-based symptom of Alzheimer's caused by brain changes that disrupt emotion regulation and by imbalances in neurotransmitters such as serotonin, norepinephrine, and dopamine. It notes caregivers often blame themselves, but agitation increases with disease progression (about 56% in early stages to 68% in moderate-to-severe stages). Environmental stressors, like large gatherings or disrupted routines, can worsen it. The piece offers practical management tips—maintaining daily routines, avoiding arguments, using calming approaches, and consulting healthcare providers about treatments—while emphasizing caregiver support and self-care.

FDA Approves Otsuka Pharma's Alzheimer's Agitation Drug
health2 years ago

FDA Approves Otsuka Pharma's Alzheimer's Agitation Drug

The FDA has approved Rexulti (brexpiprazole) oral tablets as the first treatment option for agitation associated with dementia due to Alzheimer's disease. Dementia is a serious and debilitating neurological condition characterized by progressive decline in one or more cognitive domains in the brain. Alzheimer's disease is the most common cause of dementia. The effectiveness of Rexulti for the treatment of agitation associated with dementia due to Alzheimer's disease was determined through two 12-week, randomized, double-blind, placebo-controlled, fixed-dose studies.