Single Dose of Psilocybin Offers Rapid, Lasting Relief from Pain and Depression

TL;DR Summary
A single dose of psilocybin in mice rapidly reversed chronic pain and depression-like symptoms within 24 hours, with effects lasting at least 12 days, by calming overactive neurons in the brain's anterior cingulate cortex and requiring partial activation of serotonin receptors, highlighting potential for new treatments in humans.
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- Magic Mushrooms Show Surprising Power to Ease Pain and Depression SciTechDaily
- A single dose of psilocybin may rewire the brain for lasting relief ScienceDaily
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