Aging gut bacteria linked to memory decline, hinting at gut-targeted therapies
TL;DR Summary
In ageing mice, the bacterium Parabacteroides goldsteinii proliferates and dampens gut-brain signalling, contributing to memory decline; transferring this microbe to young mice worsens memory, while wiping out gut bacteria or targeting P. goldsteinii with phage therapy restores memory, suggesting gut-directed treatments could combat age-related cognitive decline if the mechanism also exists in humans.
- Memory loss is fuelled by gut microbes in ageing mice Nature
- Intestinal interoceptive dysfunction drives age-associated cognitive decline Nature
- The gut microbiome may influence brain aging, mouse study suggests Scientific American
- Common and inexpensive supplement quickly improves memory and prevents dementia Earth.com
- Reversing Memory Loss via the Vagus Nerve Neuroscience News
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