"Chemists revolutionize drug discovery with carbon-to-nitrogen atom swap"

TL;DR Summary
Chemists at the University of Chicago have made a breakthrough in drug discovery chemistry by developing two methods to replace a carbon atom with a nitrogen atom in a molecule. These methods address a long-standing challenge in pharmaceutical chemistry and could make it easier to develop new drugs. One method works on molecules that already have a nearby nitrogen atom, while the other method can remove a carbon atom and replace it with nitrogen. Although the techniques are not perfect yet, they provide a promising way forward for drug development.
Topics:top-news#chemistry#drug-discovery#molecule#nitrogen-atom#science-and-technology#university-of-chicago
- Chemists make breakthrough in drug discovery chemistry: Two methods to replace carbon with a nitrogen atom in a molecule Phys.org
- Carbon-to-nitrogen single-atom transmutation of azaarenes Nature.com
- UChicago chemists make breakthrough in drug discovery chemistry UChicago News
- Atom-swap chemistry could aid drug discovery Nature.com
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