"Chemists revolutionize drug discovery with carbon-to-nitrogen atom swap"
Chemists at the University of Chicago have made a breakthrough in drug discovery chemistry by developing two methods to replace a carbon atom with a nitrogen atom in a molecule. These methods address a long-standing challenge in pharmaceutical chemistry and could make it easier to develop new drugs. One method works on molecules that already have a nearby nitrogen atom, while the other method can remove a carbon atom and replace it with nitrogen. Although the techniques are not perfect yet, they provide a promising way forward for drug development.