The Synergy of AI and CRISPR: Revolutionizing Gene Editing and RNA-Targeting

Researchers have developed an artificial intelligence model, TIGER, that can accurately predict the on- and off-target activity of RNA-targeting CRISPR tools. This innovation has the potential to revolutionize the development of CRISPR-based therapies by facilitating precise control of gene expression. The model combines deep learning with CRISPR screens to design guide RNAs and modulate gene expression, offering new possibilities for treating genetic diseases and developing RNA-targeting therapies.