Tag

Gene Modulation

All articles tagged with #gene modulation

science-and-technology2 years ago

The Synergy of AI and CRISPR: Revolutionizing Gene Editing and RNA-Targeting

Researchers have developed an artificial intelligence model, TIGER, that can accurately predict the on- and off-target activity of RNA-targeting CRISPR tools. This innovation has the potential to revolutionize the development of CRISPR-based therapies by facilitating precise control of gene expression. The model combines deep learning with CRISPR screens to design guide RNAs and modulate gene expression, offering new possibilities for treating genetic diseases and developing RNA-targeting therapies.

health2 years ago

Immune cell response to non-nutritive sweeteners revealed in study.

A pilot study conducted by the Leibniz Institute for Food Systems Biology at the Technical University of Munich found that even dietary intake levels of non-nutritive sweeteners, such as saccharin, acesulfame-K, and cyclamate, can modulate the copy rate of various genes in white blood cells, sensitizing them to certain immune stimuli. The study also suggests that taste receptors may act as sweetener sensors of the cellular immune system. Further research is needed to determine the health implications of these findings.