Tag

Rna Targeting

All articles tagged with #rna targeting

science-and-technology2 years ago•6 min saved

AI Revolutionizes Gene Therapy with Precise RNA-Targeting CRISPR

Researchers have developed a deep learning model called TIGER that accurately predicts the on- and off-target activity of RNA-targeting CRISPR tools. This AI-powered approach allows for precise modulation of gene activity in human cells, potentially revolutionizing gene therapy. By minimizing off-target effects, TIGER's predictions could improve the design of CRISPR therapies, offering new treatment options for diseases caused by over-expression of certain genes or providing a novel way to combat viral infections. The study highlights the potential of combining artificial intelligence with RNA-targeting CRISPR screens to advance the development of RNA-targeting therapies.

via Neuroscience News|

#ai #crispr #deep-learning

science-and-technology2 years ago•5 min saved

The Synergy of AI and CRISPR: Revolutionizing Gene Editing and RNA-Targeting

Researchers have developed an artificial intelligence model, TIGER, that can accurately predict the on- and off-target activity of RNA-targeting CRISPR tools. This innovation has the potential to revolutionize the development of CRISPR-based therapies by facilitating precise control of gene expression. The model combines deep learning with CRISPR screens to design guide RNAs and modulate gene expression, offering new possibilities for treating genetic diseases and developing RNA-targeting therapies.

via SciTechDaily|

#artificial-intelligence #crispr #gene-modulation

science-and-technology2 years ago•5 min saved

AI's Role in Revolutionizing Gene Therapy: Predicting and Controlling CRISPR's RNA-Targeting Effects

Researchers have combined artificial intelligence (AI) with CRISPR technology to precisely control gene expression by targeting RNA instead of DNA. The study utilized a deep learning model called TIGER (Targeted Inhibition of Gene Expression via guide RNA design) to predict both on-target and off-target activity of RNA-targeting CRISPRs, outperforming previous models. This advancement could lead to the development of new CRISPR-based therapies and enable the modulation of gene dosage for various diseases. The researchers envision that AI predictions will help avoid undesired off-target CRISPR activity and further advance RNA-targeting therapies.

via Phys.org|

#ai #crispr #deep-learning