Revolutionary Approach Boosts Drug Potency with Ease

Researchers at Penn State have developed a safe and practical method to create cyclopropanes, a chemical structure that increases the potency of drugs. Cyclopropanes are found in many FDA-approved drugs, including those used to treat COVID-19, asthma, hepatitis C, and HIV/AIDS. The traditional methods for creating cyclopropanes are limited and require reactive ingredients, but the new method uses visible light and common chemical ingredients, making it accessible and efficient. The researchers successfully transformed a variety of compounds into cyclopropanes, including pharmaceutically relevant ones. The method has the potential to revolutionize drug development and creation.