Tag

Cyclopropanes

All articles tagged with #cyclopropanes

science-and-technology2 years ago

"Breakthrough Method Enhances Drug Potency and HIV Inhibition"

Researchers from Penn State have developed a safe and efficient method for creating cyclopropanes, which are important chemical structures found in many drugs. The traditional methods for creating cyclopropanes are limited and require highly reactive ingredients. The new method uses a previously undescribed chemical process that utilizes visible light and common chemical ingredients, including oxygen. It bypasses the need for unstable ingredients and produces cyclopropanes on a wide variety of molecules. This breakthrough could have significant implications for drug development and creation.

science-and-technology2 years ago

Revolutionary Approach Boosts Drug Potency with Ease

Researchers at Penn State have developed a safe and practical method to create cyclopropanes, a chemical structure that increases the potency of drugs. Cyclopropanes are found in many FDA-approved drugs, including those used to treat COVID-19, asthma, hepatitis C, and HIV/AIDS. The traditional methods for creating cyclopropanes are limited and require reactive ingredients, but the new method uses visible light and common chemical ingredients, making it accessible and efficient. The researchers successfully transformed a variety of compounds into cyclopropanes, including pharmaceutically relevant ones. The method has the potential to revolutionize drug development and creation.