"Cracking the Code: David Sinclair's Groundbreaking Theory on Aging"

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Source: Lifespan.io News
"Cracking the Code: David Sinclair's Groundbreaking Theory on Aging"
Photo: Lifespan.io News
TL;DR Summary

Geroscientist David Sinclair presents his "Information Theory of Aging," which argues that epigenetic changes, rather than DNA mutations, are the underlying cause of aging. The theory suggests that the loss of regulatory epigenetic information leads to cellular confusion and dysfunction, contributing to the manifestations of aging. Sinclair highlights the potential of cellular reprogramming techniques to reverse epigenetic dysregulation and rejuvenate cells. The theory draws inspiration from Claude Shannon's information theory of communication and proposes the existence of "passive" and "active" observer molecules that could preserve and correct epigenetic changes.

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