Advancements in CRISPR technology revolutionize gene editing and viral engineering
TL;DR Summary
Scientists have developed a new CRISPR-based gene-editing tool called AsCas12f, which is one-third the size of the commonly used Cas9 enzyme. The smaller size allows for more efficient delivery into living cells, potentially leading to improved treatments for patients with genetic disorders. The engineered AsCas12f enzyme has been shown to have 10 times more editing ability than the original unmutated type and has been successfully tested in mice. This development could pave the way for more effective gene therapies in the future.
Topics:science#ascas12f#crispr#gene-editing#genetic-disorders#patient-treatment#science-and-technology
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- CRISPR-based gene editing gets smaller, better "scissors" Interesting Engineering
- Using a cutting enzyme and an RNA repair enzyme to modify RNA virus genomes Phys.org
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