Nanobody Targets HSV Glycoprotein B to Neutralize Herpes Viruses

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Source: Nature
Nanobody Targets HSV Glycoprotein B to Neutralize Herpes Viruses
Photo: Nature
TL;DR Summary

Researchers developed a prefusion-specific nanobody that neutralizes HSV-1 and HSV-2 by binding to glycoprotein B, preventing its conformational change necessary for viral fusion, with detailed structural insights provided by cryo-EM.

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