Nanobody Targets HSV Glycoprotein B to Neutralize Herpes Viruses

TL;DR Summary
Researchers developed a prefusion-specific nanobody that neutralizes HSV-1 and HSV-2 by binding to glycoprotein B, preventing its conformational change necessary for viral fusion, with detailed structural insights provided by cryo-EM.
- A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 Nature
- Nanobody Against Herpes The National Tribune
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