NAD+-Driven Therapy Reverses Alzheimer’s Memory Loss in Mouse Models

Scientists reversed Alzheimer’s-related memory loss in two mouse models by restoring the brain’s energy balance with an experimental drug (P7C3-A20) that supports NAD+. Treated mice regrew cognitive function, showed fewer markers of brain damage, and had a repaired blood-brain barrier; human brain tissue data similarly linked NAD+ imbalance to disease. Researchers plan carefully designed human trials using blood-based biomarkers to monitor brain changes, while cautioning against DIY NAD+ boosting.