Cat Cancer Map Reveals Shared Genetic Drivers with Humans and Dogs

An international study published in Science maps the first large-scale genetic landscape of domestic-cat cancers, revealing shared driver genes with humans and dogs—most notably FBXW7 in feline mammary tumors—and suggesting cross-species insights for prevention and therapy; preliminary data also hint that FBXW7 mutations influence chemotherapy responses, and a public data resource has been released to advance feline oncology and its relevance to human cancer under a One Medicine approach.