Gene "Fingerprint" and Protein Player Reverse Brain Aging and Restore Memory

A study conducted on mice by Stanford scientists has identified significant molecular changes in the white matter of aging brains, which is responsible for transmitting brain signals. The research also found that plasma from young mice could potentially slow age-related cognitive decline. These findings provide insights into normal brain aging and neurodegenerative diseases such as Alzheimer's and Parkinson's. The study examined gene expression in different regions of the mouse brain and identified 82 genes that vary in concentration with age. The researchers also explored interventions such as caloric restriction and plasma injections to protect against age-related gene expression shifts. This study could lead to new treatments and interventions for neurodegenerative diseases and age-related cognitive decline.