The Impact of mRNA Transport on Neuronal Well-being

Researchers have discovered a link between mRNA transport and the survival and pathology of sensory neurons. They found that the Dynein Roadblock 1 (Dynlrb1) subunit of the dynein protein complex is critical for neuron survival and the transport of vital molecules. They also identified the role of FMRP in mRNA transport, which offers a more energy-efficient method than transporting proteins. Dysfunctions in this system could provide insights into certain neuropathologies.