The Impact of Cortisol and the Mediterranean Diet on PTSD

A study conducted by researchers at EPFL has shed light on the role of stress-induced hormones, such as cortisol, in the development of post-traumatic stress disorder (PTSD). Using a rat model with a blunted hormonal response to stress, the researchers observed impaired fear extinction, reduced hippocampal volume, and sleep disturbances, all of which are traits associated with PTSD. The study also found that treatment combining cognitive therapy with corticosterone helped alleviate these symptoms, offering potential insights into interventions for PTSD. The research highlights the importance of glucocorticoid levels in determining vulnerability to PTSD and suggests that enhancing these levels post-trauma could potentially mitigate symptoms and improve recovery.