"Brain Receptor Linking Anxiety and Testosterone Discovered in New Study"

A study led by Prof. Shira Knafo at Ben-Gurion University has revealed a significant link between anxiety disorders and the brain receptor TACR3, as well as testosterone. The research found that rodents with high anxiety had low TACR3 levels in the hippocampus, and that testosterone deficiency-related anxiety could be addressed by targeting TACR3. The study employed innovative tools to advance understanding of synaptic plasticity and its role in anxiety, offering new therapeutic possibilities for treating anxiety disorders, especially in individuals with hypogonadism.