"Targeting Protein Pathways for Alzheimer's Treatment: Potential of Viagra and Novel Discoveries"

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Source: ScienceAlert
"Targeting Protein Pathways for Alzheimer's Treatment: Potential of Viagra and Novel Discoveries"
Photo: ScienceAlert
TL;DR Summary

Scientists have discovered that blocking the protein Mdm2 could prevent nerve damage associated with Alzheimer's disease. In experiments on mice, inhibiting Mdm2 halted the destruction of dendritic spines and synapses caused by amyloid-beta, a substance linked to Alzheimer's. While it's still early in the research, this finding offers a potential new avenue for slowing down the progression of Alzheimer's and suggests that targeting Mdm2 could be a promising approach for intervention.

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