"FDA-Approved Drugs Regenerate Insulin Production in 48 Hours: Australian Diabetes Breakthrough"

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Source: ScienceAlert
"FDA-Approved Drugs Regenerate Insulin Production in 48 Hours: Australian Diabetes Breakthrough"
Photo: ScienceAlert
TL;DR Summary

A new study has shown that FDA-approved drugs can stimulate pancreatic ductal progenitor cells to regenerate insulin-producing functions similar to β-cells, offering hope for reducing the need for insulin injections in diabetes management. The drugs target the EZH2 enzyme, allowing the ductal cells to develop insulin production and secretion capabilities. This breakthrough could potentially lead to a regenerative approach for diabetes treatment, with the ability to sense glucose levels and adjust insulin production, and it took just 48 hours of stimulation for regular insulin production to resume in tissue samples from individuals with type 1 diabetes. While clinical trials are still needed, this research presents a promising avenue for coaxing the human body to replace the functions that diabetes takes away.

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