"Revolutionary RNA Switch Offers Precise Control Over Gene Therapy"

TL;DR Summary
Researchers at Baylor College of Medicine have developed a novel gene regulation system that can turn genes on or off using FDA-approved doses of small molecules like tetracycline. This system, which operates by controlling the cleavage of a polyA signal in the RNA, promises to make gene therapy safer and more controllable, allowing for precise adjustments of therapeutic protein levels according to patient needs. The absence of foreign regulatory proteins reduces the risk of immune responses, making this a significant advancement in the field of gene therapy.
Topics:health#fda-approved#gene-regulation#gene-therapy#health-and-medicine#rna-switch#therapeutic-protein
- Novel switch turns genes on/off on cue, a promising step toward safer gene therapy Phys.org
- Scientists Create an On/Off 'Switch' for Human Genes The Daily Beast
- Gene on/off? New tech lets scientists control genes like a light switch Interesting Engineering
- An RNA-Based Switch for Dialing Gene Therapy Up or Down Genetic Engineering & Biotechnology News
- Novel RNA-Based Regulatory Switch Could Advance Gene Therapy Inside Precision Medicine
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