"Ketamine's Impact on Depressed Brain Connectivity Revealed in New Study"

New research delves into how ketamine affects brain connectivity in individuals with treatment-resistant depression, shedding light on its rapid antidepressant effects. The study, involving 50 participants, found that ketamine significantly improved depressive symptoms and the ability to anticipate pleasure compared to a placebo. Changes in brain connectivity within the anterior cingulate cortex were associated with improvements in depression and anhedonia symptoms, suggesting that different brain regions may contribute to these conditions in diverse ways. The findings provide valuable insights into the potential for targeted treatments for specific groups of patients burdened by particular symptoms.