The Genetic Link Between Reproduction and Aging

TL;DR Summary
A study utilizing data from over 276,000 people in the UK Biobank database has provided genetic evidence supporting the antagonistic pleiotropy theory of aging, which suggests that genetic mutations promoting early reproduction may also accelerate aging. The researchers found a strong negative correlation between reproduction and lifespan, indicating that genes promoting higher reproduction rates are associated with shorter lifespans. While environmental factors also play a significant role, this study highlights the trade-off between reproduction and longevity and provides genome-wide evidence for the evolutionary explanation of senescence.
- Genes Associated with Earlier and Higher Reproduction Linked to Accelerated Aging Neuroscience News
- Gene variants that promote having more sex and kids diminish your life span Ars Technica
- Genes That Boost Fertility Also Shorten Our Life, Study Suggests The New York Times
- Having children earlier in life is genetically linked to dying younger New Scientist
- Evidence for the role of selection for reproductively advantageous alleles in human aging Science
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