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Tubb4b Gene

All articles tagged with #tubb4b gene

neuroscience1 year ago

"Uncovering the Genetic Basis of Left-Handedness and Neurological Disorders"

A study using UK Biobank data has identified rare variants in the TUBB4B gene significantly associated with left-handedness, shedding light on the genetic basis of this trait and its link to neurodevelopmental disorders. Despite the influence of these rare genetic variants, they account for less than 1% of the heritability of left-handedness, indicating a complex interplay of factors in determining this trait. The findings offer insights into the genetic intricacies of left-handedness and its connection to brain asymmetry and neurodevelopmental disorders, providing new avenues for investigating the developmental pathways leading to brain asymmetry.

science1 year ago

"Unraveling the Genetic Basis of Left-Handedness"

A new study sheds light on a genetic component of left-handedness, identifying rare variants of the TUBB4B gene that are 2.7 times more common in left-handed people. These variants may play a role in the development of brain asymmetry that determines dominant hand. The findings, based on genetic data from over 350,000 adults, suggest that microtubules controlled by TUBB4B are involved in setting up the brain's normal asymmetries. The prevalence of left-handedness varies globally, possibly reflecting cultural suppression. The study's findings may have relevance in psychiatry, as genes involved in brain asymmetry may also be linked to psychiatric traits.

science1 year ago

"Uncovering the Genetic Link to Left-Handedness"

A new study has identified rare genetic variants of the TUBB4B gene that are 2.7 times more common in left-handed individuals, shedding light on the genetic component of left-handedness. These variants may play a role in the development of brain asymmetry that determines dominant hand. The findings, based on genetic data from over 350,000 adults, suggest that microtubules controlled by TUBB4B are involved in setting up the brain's normal asymmetries. The study also suggests a potential link between genes involved in brain asymmetry and psychiatric traits, such as schizophrenia and autism.

science1 year ago

"Uncovering the Genetic Link Between Cell Shape and Left-Handedness"

A new study sheds light on a genetic component of left-handedness, identifying rare variants of the TUBB4B gene that are 2.7 times more common in left-handed people, suggesting a role in brain asymmetry development. The gene controls a protein integrated into cells' microtubules, providing insight into the brain's normal asymmetries. The findings, based on genetic data from over 350,000 adults, may have relevance in psychiatry, as left-handedness is associated with conditions like schizophrenia and autism.