A UCLA study found that listening to music after an experience can enhance memory, especially when the emotional response is moderate, influencing whether details or the gist of the memory are better retained, highlighting music's potential as a personalized therapeutic tool.
Researchers from the University of Exeter have discovered that targeting tiny amounts of hydrogen sulfide (H2S) to specific areas of cells using a H2S-releasing molecule called AP39 can greatly improve health and activity as organisms age. By specifically targeting H2S to the mitochondria, the energy-generating machinery of cells, this approach could potentially be used as a therapeutic for healthy aging. The study, conducted on worms, found that administering AP39 improved mitochondrial integrity, kept muscles active, and extended healthspan. The research also identified a group of proteins that regulate gene expression in aging, potentially opening up new targets for therapy in age-related conditions. The underlying technology has been assigned to the spin-out company MitoRx Therapeutics, which aims to develop next-generation compounds for combating diseases of aging.
A new cancer therapeutic, combining antibody fragments with molecularly engineered nanoparticles, permanently eradicated gastric cancer in treated mice. The drug delivery system, called Cornell prime dots (C’ dots), is a versatile and adaptable treatment for various cancer types, with minimal side effects and toxicity. The C’ dots are small enough to penetrate tumors and safely pass through organs once injected into the body. The final product was a version of C’ dots, armed with cancer-targeting antibody fragments and a large drug payload, all packed into a sub-7-nanometer, drug-immune conjugate therapy – a first of its kind in that size class, according to the researchers.