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Synthetic Molecule

All articles tagged with #synthetic molecule

health2 years ago•4 min saved

Breakthrough Synthetic Antibiotic Destroys Drug-Resistant Superbugs

Scientists at Duke University have developed a synthetic molecule called LPC-233 that has shown promise in combating drug-resistant gram-negative bacteria, including Salmonella, Pseudomonas, and E. coli. The compound disrupts the synthesis of the bacterial outer membrane, leading to the bacteria's inability to survive. LPC-233 has demonstrated effectiveness in animal tests, reducing bacterial viability by 100,000-fold within four hours. It has also shown durability and the ability to reach the urinary tract, making it a potential treatment for stubborn urinary tract infections. The compound is now being prepared for phase 1 clinical trials to assess its safety and efficacy in humans.

via Medical Xpress|

#antibiotics #drug-resistant-superbugs #gram-negative-bacteria

science-and-technology2 years ago•2 min saved

Bio-inspired enzymes for hydrogen fuel production.

Researchers from the University of Illinois Urbana-Champaign have designed a synthetic molecule that mimics the hydrogen gas-producing chemical reaction performed by the ancient biological enzyme nickel-iron hydrogenase. The enzyme produces hydrogen using earth-abundant metals in its core, making it an attractive alternative to platinum, which is currently used as a catalyst in industrial hydrogen production. The team designed an organic molecule called a ligand that contains electron-donating atoms like nitrogen and sulfur, which can hold the nickel in place and support the two relevant paramagnetic states that produce hydrogen. The molecule could lead to further insights into how nature performs chemistry with small molecules like hydrogen.

via Phys.org|

#hydrogen-fuel #nickel-iron-hydrogenase #organometallic-chemistry