Tag

Survival Outcomes

All articles tagged with #survival outcomes

The Potential Risks of Lorazepam in Pancreatic Cancer Treatment

Originally Published 2 years ago — by Cancer Discovery

A study conducted by researchers at the Roswell Park Comprehensive Cancer Center has found that the use of lorazepam, a commonly prescribed anti-anxiety medication, stimulates the production of IL6, a pro-inflammatory cytokine, in pancreatic cancer cells. The study also revealed that higher levels of IL6 were associated with poorer survival outcomes in patients with pancreatic cancer. These findings suggest a potential link between lorazepam use, IL6 production, and disease progression in pancreatic cancer, highlighting the need for further research in this area.

health medical-research il6-production lorazepam medical-research pancreatic-cancer pharmacology survival-outcomes

"Autophagy protein p62: A Key Factor for Survival in Sporadic ALS"

Originally Published 2 years ago — by ALS News Today

Accumulation of p62 protein, involved in the autophagy process, in the spinal cord is associated with worse survival outcomes in individuals with sporadic amyotrophic lateral sclerosis (ALS). The buildup of p62 clumps indicates impaired autophagy, leading to the improper clearance of toxic protein aggregates contributing to ALS. The study suggests that p62 could serve as a potential prognostic biomarker in ALS.

health medical-research als autophagy medical-research motor-neurons p62-protein survival-outcomes