Researchers from MIT have discovered that sensory stimulation at a gamma frequency of 40 Hz can enhance the brain's clearance of amyloid proteins, potentially offering a new avenue for Alzheimer's treatment. This stimulation activates the brain's glymphatic system, facilitating the removal of waste from the brain. The study's findings shed light on the biological mechanisms underlying this process, highlighting the role of neuronal activity, peptide signaling, and the glymphatic system in combating neurodegenerative diseases.
A study at MIT reveals that sensory stimulation at the gamma brain rhythm frequency of 40 Hz can reduce Alzheimer's disease progression in mice by promoting the clearance of amyloid proteins via the brain's glymphatic system. Researchers found that sensory gamma stimulation prompts a specific type of neuron to release peptides, which in turn drive processes that increase amyloid clearance. The study suggests that sensory stimulation of brain rhythms may offer potential for treating neurological disorders.
MIT researchers have found that daily exposure to 40 Hz gamma frequency brain rhythm tactile stimulation improved brain health and motor function in mice and reduced key markers of Alzheimer’s disease, including levels of the hallmark Alzheimer’s protein phosphorylated tau, neural DNA damage, and neuron death. The study reinforces the potential of non-invasive sensory stimulation as a new therapeutic strategy for neurodegenerative diseases.
Non-invasive sensory stimulation of 40 Hz gamma frequency brain rhythms can reduce Alzheimer's disease pathology and symptoms, as shown in mice models. A new study by MIT scientists shows that Alzheimer's model mice exposed to 40 Hz vibration an hour a day for several weeks showed improved brain health and motor function compared to untreated controls. The stimulation can also reduce levels of the hallmark Alzheimer's protein phosphorylated tau, keep neurons from dying or losing their synapse circuit connections, and reduce neural DNA damage.
