Quetiapine News

california4 hours ago•5 min saved

Kratom-Linked Meds Cited in Beutner Daughter’s Death; Suicide Ruled

The Los Angeles County Medical Examiner ruled that 22-year-old Emily Beutner’s death was a suicide, caused by the combined effects of kratom compounds (mitragynine and 7-hydroxymitragynine) with prescription antipsychotic quetiapine and antidepressant mirtazapine; she was found by a Palmdale roadside after midnight on Jan. 6 and died after being hospitalized at 2:10 a.m. Her death occurred while her father, former LAUSD superintendent Austin Beutner, was grieving and had recently ended his bid for mayor.

via Los Angeles Times|

#california #emily-beutner #kratom

health2 years ago•3 min saved

Head-to-Head Trial Declares Esketamine Superior to Quetiapine for Treatment-Resistant Depression

A head-to-head trial sponsored by Janssen, the maker of esketamine spray, compared the effectiveness of nasal esketamine spray to quetiapine, an extended-release antipsychotic, in patients with treatment-resistant depression. The study found that esketamine was more effective than quetiapine when taken in combination with SSRIs and SNRIs. At eight weeks, 27% of patients treated with esketamine were in remission compared to 17% of those taking quetiapine. Esketamine patients in remission at week eight were more likely to remain in remission until week 32. Patients taking esketamine were also more likely to adhere to the treatment. The study suggests that a longer initial course of esketamine treatment may be more effective and calls for further research to identify patients who are likely to respond positively to the drug.

via STAT|

#antidepressants #clinical-trial #esketamine