An elderly taxi driver in Seoul was arrested after a deadly crash that killed one person and injured 13 others, with tests indicating morphine use, raising concerns about elderly drivers' safety.
Researchers at Stanford have discovered that adaptive myelination, a form of brain plasticity, contributes to drug addiction by reinforcing drug-seeking behavior. A single dose of morphine in mice triggered myelination in reward-related brain circuits, but blocking this myelination prevented addiction. This finding opens potential new avenues for addiction treatment.
The World Health Organization (WHO) has highlighted the unequal distribution of morphine worldwide, leading to millions of people suffering preventable pain. While morphine is a crucial medication for pain relief, it is predominantly used in higher-income countries, leaving lower-income countries with severe shortages due to irregular supply, local policies, lack of providers, and stigma. The report calls for affordable pricing policies, distribution hubs, and expanded access to address the disparities. The authors also acknowledge the potential harms of morphine use, including substance misuse and illicit trade, but emphasize the importance of not letting people suffer when safe and effective pain management options are available.