All articles tagged with #molecular basis
A study led by Prof. Takahashi has identified increased AMPA receptor density in the brains of Long COVID patients with cognitive impairment, linking molecular changes to brain fog and suggesting potential targets for diagnosis and treatment.
Researchers have uncovered the molecular basis of sugar detection by an insect taste receptor, shedding light on how insects discriminate between different sweet substances. Using the gustatory receptor Gr9 from the silkworm Bombyx mori, the study revealed that while both D-fructose and L-sorbose bind to the receptor, only D-fructose is capable of activating it by engaging an allosteric pathway that regulates ion conduction. The findings suggest that chemical specificity in sugar detection arises from a combination of receptor-ligand interactions and allosteric coupling, providing insight into the mechanisms underlying insect sugar perception.
Scientists have conducted a comprehensive proteomic study analyzing approximately 10,000 proteins involved in 10 different types of cancer, revealing insights into the proteins and their regulatory networks that drive tumor growth. This research goes beyond genetic information and sheds light on how cancer grows and spreads, offering potential for new therapies that can block key proteins or trigger immune responses. The study also explains why some patients may not respond to existing immunotherapies. Understanding the molecular basis of cancer at the protein level could pave the way for novel treatments.