Researchers at Mount Sinai have uncovered detailed molecular insights into the 5-HT1A serotonin receptor, revealing how it interacts with G proteins and drugs, which could lead to the development of faster, more targeted mental health treatments with fewer side effects.
Some psychiatrists are prescribing the diabetes medication Ozempic, and similar drugs, to counteract the weight gain that often occurs as a side effect of antipsychotics and certain antidepressants. While some mental health facilities and psychiatric departments are recommending or prescribing these weight-loss drugs, others have concerns about safety and side effects, as there is limited data on their use in patients with serious mental illnesses. Patients who experience significant weight gain on psychiatric medications can face increased health risks, and the weight-loss drugs offer a potential solution. However, there are ongoing debates about the risks and benefits of prescribing these medications to a vulnerable population.