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Islet Cells

All articles tagged with #islet cells

Stanford Study Reverses Type 1 Diabetes in Mice with Dual-Transplant, No Immunosuppression
science3 hours ago

Stanford Study Reverses Type 1 Diabetes in Mice with Dual-Transplant, No Immunosuppression

Stanford researchers cured type-1 diabetes in mice for six months using a dual transplant of pancreatic islet cells and donor hematopoietic stem cells to create a hybrid immune system, eliminating the need for insulin or immune-suppressing drugs. In the study, 19 of 19 treated mice remained diabetes-free and 9 of 9 long-standing diabetics were cured, though translating the approach to humans will require overcoming donor cell sourcing and scaling challenges.

Revolutionary Under-Skin Implant Reverses Type 1 Diabetes Without Drugs
health2 years ago

Revolutionary Under-Skin Implant Reverses Type 1 Diabetes Without Drugs

Researchers from Cornell and the University of Alberta have developed a new technique to treat Type 1 diabetes by implanting a device under the skin that can secrete insulin without the need for immunosuppression. The device, named SHEATH (Subcutaneous Host-Enabled Alginate THread), is inserted into a pocket created by nylon catheters, allowing blood vessels to form around it. The device provides a long-term and less invasive alternative to insulin injections or traditional transplants, and future versions may last for two to five years before needing replacement. Additional research is needed to support long-term functionality in large-animal models and eventually patients.