Stanford Study Reverses Type 1 Diabetes in Mice with Dual-Transplant, No Immunosuppression

Stanford researchers cured type-1 diabetes in mice for six months using a dual transplant of pancreatic islet cells and donor hematopoietic stem cells to create a hybrid immune system, eliminating the need for insulin or immune-suppressing drugs. In the study, 19 of 19 treated mice remained diabetes-free and 9 of 9 long-standing diabetics were cured, though translating the approach to humans will require overcoming donor cell sourcing and scaling challenges.