Tag

Hemorrhage

All articles tagged with #hemorrhage

medical-research2 years ago•25 min saved

"Revolutionizing Trauma Treatment: High-Dose Cryoprecipitate for Hemorrhage"

A randomized clinical trial involving 1604 patients with trauma and bleeding found that the addition of early and empirical high-dose cryoprecipitate to standard care did not improve all-cause 28-day mortality. There was no difference in safety outcomes, transfusion requirements, or incidence of thrombotic events between the study groups. However, subgroup analysis showed that in patients with penetrating trauma, the use of cryoprecipitate was associated with higher mortality compared to standard care.

via JAMA Network|

#clinical-trial #cryoprecipitate #hemorrhage

medical-research2 years ago•25 min saved

"Revolutionizing Emergency Care: Aortic Occlusion Saves Lives"

A bayesian randomized clinical trial conducted at 16 major trauma centers in the UK found that the addition of resuscitative endovascular balloon occlusion of the aorta (REBOA) to standard care did not reduce, and may have increased, mortality in trauma patients with exsanguinating hemorrhage. The trial included 89 patients followed up for 90 days, and the all-cause mortality was 54% in the REBOA and standard care group compared to 42% in the standard care alone group. The findings suggest that the strategy of REBOA and standard care in the emergency department does not improve outcomes for these patients.

via JAMA Network|

#emergency-department #hemorrhage #medical-research