All articles tagged with #hearing restoration
A new gene therapy using a modified virus has successfully restored hearing in teens and adults with OTOF-related congenital deafness, showing promising results especially in children aged 5-8, with significant safety and efficacy observed over a 12-month period.
A new gene therapy using a synthetic virus has successfully restored hearing in children, teenagers, and adults with a genetic form of deafness caused by OTOF mutations, showing significant improvements within six months and with no serious side effects, offering hope for broader treatments in the future.
A groundbreaking clinical trial demonstrates that gene therapy using a modified virus can successfully restore hearing in children and young adults with OTOF-related deafness, showing promising safety and efficacy, especially in children aged five to eight, marking a significant advancement in treating genetic hearing loss.
A gene therapy trial has successfully restored hearing in both ears for five children born deaf due to genetic mutations. Conducted by doctors at Fudan University in Shanghai and co-led by Massachusetts Eye and Ear, the therapy uses an inactive virus to deliver working copies of the Otof gene to the inner ear. The children, aged between one and 11, showed significant improvements in hearing and speech recognition within weeks. The trial's success raises hopes for broader applications of gene therapy in treating various forms of deafness.
A new study has demonstrated the effectiveness of gene therapy in restoring hearing function for children with hereditary deafness caused by mutations of the OTOF gene. In a trial of six children, the gene therapy was found to be an effective treatment, resulting in dramatic improvements in speech perception and the ability to conduct normal conversation. This research represents the first human clinical trial to administer gene therapy for this condition, with promising results that could potentially benefit other forms of genetic hearing loss.
Researchers have discovered a new method to deliver gene therapy through cerebrospinal fluid to restore hearing in deaf mice by repairing inner ear hair cells. By utilizing the brain's natural fluid flow and a little-understood passage called the cochlear aqueduct, the scientists successfully restored hearing in adult deaf mice. This breakthrough may pave the way for using gene therapy to restore hearing in humans with genetic-mediated hearing loss.
Researchers have discovered a new method to deliver gene therapy into the inner ear by utilizing the natural flow of cerebrospinal fluid through a little understood passage called the cochlear aqueduct. By injecting an adeno-associated virus into the cerebrospinal fluid, the researchers were able to deliver a gene therapy that repaired inner ear hair cells and restored hearing in adult deaf mice. This breakthrough could pave the way for future gene therapies to restore hearing in humans with genetic-mediated hearing loss.