A phase 3 study in Chinese adults with type 2 diabetes found that mazdutide, a dual glucagon and GLP-1 receptor agonist, was more effective than dulaglutide in reducing HbA1c and body weight over 28 weeks, with manageable gastrointestinal side effects.
A study reviewing 11 research papers found that weight loss achieved through anti-obesity medications like Ozempic often reverses within weeks after stopping the drugs, with an average regain of 2.5 kg over 20 weeks, highlighting challenges in maintaining weight loss post-treatment.
Scientists are developing a drug-free weight loss pill that tricks the body into feeling full, potentially offering a safe alternative to existing weight loss drugs. The experimental capsule, which contains nutrients from sources like broccoli and coconut oil, has shown promising early results in reducing food intake. The pill aims to address the global obesity crisis by targeting the glucagon-like peptide-1 hormone. While further trials are needed, the potential for a natural, clinically proven weight loss solution is being explored amidst concerns about the long-term effectiveness and safety of current weight loss injections.