Tag

Genetic

All articles tagged with #genetic

medical-science-news2 years ago

Revolutionary Nanowire Technology Enables Non-Invasive cfDNA Capture and Release from Urine

Researchers at Nagoya University in Japan have developed a technology to capture and release cell-free DNA (cfDNA) on nanowire surfaces from urine, allowing for the detection of genetic mutations associated with gliomas, a type of brain tumor. The technique overcomes the challenge of isolating cfDNA from urine samples and could potentially be used for early cancer detection. The researchers successfully detected the IDH1 mutation, a characteristic genetic mutation found in gliomas, from a small urine sample. This method opens up possibilities for detecting other types of tumor mutations that cannot be isolated by conventional methods.

genomics2 years ago

New Human Pangenome Reference Enhances Chromosome Biology Understanding.

Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human pangenome reference. The draft pangenome uses complete genome assemblies to provide a diverse look at the genetic makeup of humans. The pangenome project aims to map the entirety of human genetic variation to create a comprehensive reference for geneticists to use to compare DNA sequences, which can aid in the study of connections between genes and diseases. The UTHSC researchers discovered different acrocentric chromosomes can recombine with each other to exchange DNA through their shorter arms, which was key to solving the most common type of chromosomal abnormality in humans.