Tag

Geneexpression

All articles tagged with #geneexpression

health-and-nutrition2 years ago

"Exploring the Health Implications of High-Fat Diets on Body and Microbiome"

A UC Riverside study has found that high-fat diets, including those with fats from plant sources like soybean and coconut oil, can lead to negative changes in gene expression related to obesity, colon cancer, immune system function, and brain health. The research, conducted on mice, showed that diets with at least 40% of calories from fat altered the microbiome and increased the expression of genes that could affect susceptibility to infectious diseases, including COVID-19. The study suggests that even plant-based high-fat diets can be detrimental and emphasizes the importance of moderation in dietary fat intake.

science-and-health2 years ago

"Unveiling the Impact of Sex Chromosomes on Gene Expression Across the Body"

A study by David Page and Adrianna San Roman has shown that sex chromosomes, particularly through the gene pair ZFX and ZFY, have a significant regulatory effect on gene expression throughout the human body, not just in sexual differentiation. This challenges the traditional understanding of X and Y chromosomes, revealing their roles as global gene regulators. The research utilized natural variations in sex chromosome composition in humans to demonstrate how these chromosomes modulate the expression of thousands of genes across different cell types, potentially contributing to sex differences in health and disease. The findings suggest a reevaluation of the X and Y chromosomes' genetic impact, highlighting the importance of the 'inactive' X and 'gene-poor' Y chromosomes in gene regulation.

science2 years ago

The Impact of Space Travel on Astronauts' Immune System

A study involving 14 astronauts who spent 4½ to 6½ months aboard the International Space Station found that gene expression in white blood cells crucial to the immune system quickly decreased when they reached space and then returned to normal not long after returning to Earth. This weakened immunity increases the risk of infectious diseases limiting astronauts' ability to perform their very demanding work in space. The findings offer insight into why astronauts are more susceptible to infection during flights, showing how the body's system for fighting off pathogens is weakened in space.